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Publications
Clinical Publications
C. Pfleger, G. Meierhoff, H. Kolb, and N.C. Schloot “Association of T-cell reactivity with beta-cell function in recent onset type 1 diabetes patients.” J Autoimmun. 2010 Mar;34(2):127-35.
B. Fischer, D. Elias, R.G. Bretzel, and T Linn. “Immunomodulation with heat shock protein DiaPep277 to preserve beta cell function in type 1 diabetes - an update.” Expert Opin Biol Ther. 2010 Feb(2):265-72
P.Pozzilli and R.D. Leslie “New prospects for immunotherapy at diagnosis of type 1 diabetes.” Diabetes Metab Res Rev. 2009 May;25(4):299-301.
R. Eldor, S. Kassem, I. Raz. “Immune modulation in type 1 diabetes mellitus using DiaPep277: a short review and update of recent clinical trial results.” Diabetes Metab Res Rev. 2009;May;25(4):316-20.
V. A. L. Huurman, P.E. van der Meide, G. Duinkerken, S. Willemen, I.R. Cohen, D. Elias, and B.O. Roep. “Immunological efficacy of heat shock protein 60 peptide DiaPep277TM therapy in clinical type 1 diabetes.” Clin Exp Immunol. 2008 June;152(3):488-497.
N.C. Schloot, G. Meierhoff, C. Lengyel, G. Vándorfi, J. Takács, P. Pánczél, L. Barkai, L. Madácsy, T. Oroszlán, P. Kovács, G. Sütö, T. Battelino, N. Hosszufalusi, and G. Jermendy. “Effect of heat shock protein peptide DiaPep277 on ß-cell function in paediatric and adult patients with recent-onset diabetes mellitus type 1: two prospective, randomized, double-blind phase II trials.” Diabetes Metab Res Rev 2007 May;23:276-285.
Raz, A. Avron, M. Tamir, M. Metzger, L. Symer, R. Eldor, I.R. Cohen, and D. Elias. “Treatment of new-onset type 1 diabetes with peptide DiaPep277 is safe and associated with preserved ß-cell function: extension of a randomized, double-blind, phase II trial.” Diabetes Metab Res Rev 2007 May;23:292-298.
P. Pozzilli “Immuno-intervention and preservation of beta-cell function in type 1 diabetes.” Diabetes Metab Res Rev 2007 May;23:255-256.
L. Lazar, R. Ofan, N. Weintrob, A. Avron, M. Tamir, D. Elias, M. Phillip and Z. Josefsberg. “Heat-shock protein peptide DiaPep277 treatment in children with newly diagnosed type 1 diabetes: a randomised, double-blind phase II study.” Diabetes Metab Res Rev 2007 May;23(4):286-291.
V.A.L. Huurman, K. Decochez, C. Mathieu, I.R. Cohen and B.O. Roep. “Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients.” Diabetes Metab Res Rev 2007 May;23(4):269-275.
D. Elias, A. Avron, M. Tamir, and I. Raz. “DiaPep277 Preserves Endogenous Insulin Production by Immunomodulation in Type 1 Diabetes.” Ann. N.Y. Acad. Sci. 2006 Oct; 1079: 340-344.
Raz, I., D. Elias, A. Avron, M. Tamir, M. Metzger, and I.R. Cohen. “Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial.” Lancet 2001 Nov;358:1749-1753.
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